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Mitochondria: Structures, Functions, Oscillations, and EMF

EMF and Mitochondria>

Mind Map branch: Mitochondria: Structures, Functions, Oscillations, and EMF Mitochondria:
Structures, Functions, 
Oscillations,
and
EMF What are mitochondria? http://www.mitochondrial.net/ Mitochondria.net http://en.wikipedia.org/wiki/Mitochondrion Wiki description, images http://www.ncbi.nlm.nih.gov/pubmed/15302203 Center stage in cell biology Mitochondrial oscillators http://www.ncbi.nlm.nih.gov/pubmed/18760283?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_SingleItemSupl.Pubmed_Discovery_RA&linkpos=2&log$=relatedarticles&logdbfrom=pubmed Glutathione oxidation trigger http://www.ncbi.nlm.nih.gov/pubmed/15345581?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_SingleItemSupl.Pubmed_Discovery_RA&linkpos=2&log$=relatedarticles&logdbfrom=pubmed Oscillator dependent on ROS http://jxb.oxfordjournals.org/cgi/content/abstract/10/2/330 Small systems, chemical reactions oscillate http://www.ncbi.nlm.nih.gov/pubmed/18783175 Mito oscillations in physiology and pathology http://www.ncbi.nlm.nih.gov/pubmed/15302557 Mitochondrial reticulum, natural EM response http://www.ncbi.nlm.nih.gov/pubmed/20206123 Mitochondrial oscillators, ROS communications EMF studies http://www.ncbi.nlm.nih.gov/pubmed/17613036 ELF, degeneration http://www.ncbi.nlm.nih.gov/pubmed/16988914 ELF, missing cristae http://www.ncbi.nlm.nih.gov/pubmed/19879861 RF/MW, DNA damage http://www.ncbi.nlm.nih.gov/pubmed/3405087 EF, liver cell mitochondria http://www.ncbi.nlm.nih.gov/pubmed/20017630 ELF, swelling, chrystallization http://www.ncbi.nlm.nih.gov/pubmed/6256801 EF, respiratory activity changes http://www.ncbi.nlm.nih.gov/pubmed/2453777 ELF, RNA and protein changes http://www.ncbi.nlm.nih.gov/pubmed/8714296 HF, cytochrome oxidase effects http://www.ncbi.nlm.nih.gov/pubmed/14689206 ELF, alteration of DNA synthesis http://www.ncbi.nlm.nih.gov/pubmed/3603741 ELF, mitochondrial lipid changes http://www.ncbi.nlm.nih.gov/pubmed/3207391 RF/MW edematous mitochondria http://www.ncbi.nlm.nih.gov/pubmed/14694650 EMP, membrane lipid peroxidation http://www.ncbi.nlm.nih.gov/pubmed/7387414 HF, peripheral, central mitochondria http://www.ncbi.nlm.nih.gov/pubmed/1209775 UHF, SHF, oxphos changes, swelling http://www.ncbi.nlm.nih.gov/pubmed/1487932 EM, intracellular respiratory chain effects http://www.ncbi.nlm.nih.gov/pubmed/10588063 EMF, varying organelle responses to fields http://www.ncbi.nlm.nih.gov/pubmed/16239325 EF, mito membranes more vulnerable than cell membranes http://www.ncbi.nlm.nih.gov/pubmed/20690107 ELF, effects on human sperm motility mediated by mitochondria

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MITOCHONDRIA -- TINY ORGANELLES FOUND IN ALMOST ALL CELLS OF THE BODY -- CREATE ALMOST ALL OF THE ENERGY REQUIRED BY THE BODY. THEY NATURALLY OSCILLATE IN A DELICATE BALANCE OF FREE RADICAL GENERATION AND SCAVENGING. WHEN THIS BALANCE SHIFTS, DYSFUNCTION AND PATHOLOGY RESULT.

EMF HAS BEEN SHOWN TO AFFECT MITOCHONDRIAL FUNCTION AND STRUCTURE. DEPENDING UPON THE ABILITY OF THESE TINY ORGANELLES TO RESPOND TO THIS KIND OF PHYSIOLOGIC STRESS, AND THE SUBSTRATES AVAILABLE FOR ATP SYNTHESIS TO PROVIDE ENERGY FOR CELLULAR RESPONSES, THE EFFECTS ON LIVING SYSTEMS MAY VARY FROM NO SYMPTOMS TO SERIOUS DISEASE.

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Mitochondria,
in cell and enlarged

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PUTTING SOME PIECES TOGETHER ABOUT EMF EFFECTS ON US

We know the effects of EMF on our tissues are nonlinear.
We know that free radicals are created during EMF exposures.
We know that DNA and RNA are damaged.
We know that calcium movement is altered.
We know that energy is required to respond to these effects.
We know that mitochondria have their own DNA.
We know the mitochondria create most of our cellular energy (ATP).
We know mitochondria have other very important functions in cells.
We know mitochondrial structures are vulnerable to EMF.
We know that mitochondria naturally oscillate as they work.
We don't know if EMF directly alters mitochondrial oscillations.
We know that free radical shifts will disturb oscillations.
We know that oscillatory disturbance is associated with pathology.

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Ball and stick
model of ATP

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EARLY ATP DECREASE
Some reported signs

Aging
Fatigue
Fibromyalgia
Shortness of breath
Soreness after exercise
Healing, repair slows down

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