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Biofilms: An Introduction

Biofilms: An Introduction>

Mind Map branch: Biofilms: An Introduction http://www.erc.montana.edu/MultiCellStrat/default.html Biofilms:
An
Introduction http://en.wikipedia.org/wiki/Biofilms Overview Bacteria are either free-floating or in biofilms There are several steps from bacteria to biofilm There must be a surface, bacteria, and water Early attachment reversible, becomes irreversible Eventually a mix of organisms Bacteria Archaea Protozoa Fungi Algae Community behaviors May fossilize Quorum sensing behavior Each type of organism has its own function Creation of sticky matrix, the exopolysaccaride (EPS) EPS facilitates protection, communication, nutrition Sensitivity to chemical and physiologic manipulation Resistant to antiseptics 1500 X as much antibiotic needed Matrix protects against macrophages Enzymes may disrupt matrix Radiation may detach, deactivate organisms "Persister" organisms begin re-colonization Sensitivity to electromagnetic radiation http://www.ncbi.nlm.nih.gov/pubmed/15620839?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Bio-magnetism and cell adhesion http://www.ncbi.nlm.nih.gov/pubmed/17178571?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Pulsed electric field shape and biofilm growth http://www.ncbi.nlm.nih.gov/pubmed/18080346?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Cathodes vs. anodes:  detachment vs. deactivation http://www.ncbi.nlm.nih.gov/pubmed/17283948?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Microwave radiation increases biofilm activity in waste recycling Links http://www.ehponline.org/realfiles/docs/1998/106-12/innovations.html Studying slime http://www.erc.montana.edu/CBEssentials-SW/bf-basics-99/bbasics-01.htm Biofilm basics http://meeting.aps.org/Meeting/MAR08/Event/81750 Knock-out gene study http://www.cs.montana.edu/ross/personal/intro-biofilms-s3.htm Introduction to biofilms http://www.plasticsurgeryinflorida.com/blog/2009/05/asaps-2009-breast-implants-biofilms.html Breast implant biofilms http://www.protherainc.com/archives/DidYouKnow/2008/12/Biofilm/biofilm.asp Biofilm disruption by enzymes http://digitalcommons.unl.edu/cgi/viewcontent.cgi?article=1031&context=rurals Biofilms on plastic cutting boards http://jmm.sgmjournals.org/cgi/content/full/55/8/999 Enzymes and biofilm degradation http://www.ncbi.nlm.nih.gov/pubmed/16353112?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=5&log$=relatedreviews&logdbfrom=pubmed Common implant persistent infections

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http://www.erc.montana.edu/MultiCellStrat/default.html

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"Biofilm is a microbial derived sessile community characterized by cells that are irreversibly attached to a substratum or interface to each other, embedded in a matrix of extracellular polymeric substances that they have produced.

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JW Costerton, L Montanaro, CR Arciola

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SOME "GOOD" EFFECTS

Waste-water treatment
Clean-up of oil spills
Providing nutrients for plants
Helping our digestion

SOME "BAD" EFFECTS

Eutrophication of waterways
Clogging of drains
Infection and inflammation
Colonization of household items
Colonization of body implants

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BIOFILMS ARE UBIQUITOUS MICROBIAL ECOSYSTEMS. THEY LIVE IN OUR WORLD, ON OUR BODIES, AND IN OUR BODIES. SOME ARE BELIEVED TO BE NECESSARY TO HUMAN LIFE, AND SOME ARE BELIEVED TO BE HARMFUL.

THERE IS A LOT OF RESEARCH TODAY IN THE AREAS OF MEDICINE, PUBLIC HEALTH, WASTE RECYCLING, BIOFUEL PRODUCTION AND BIODIVERSITY.

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The report, "Global Environmental Change: Microbial Contributions, Microbial Solutions," points out: ". . .the basic chemistry of Earth's surface is determined by biological activity, especially that of the many trillions of microbes in soil and water. Microbes make up the majority of the living biomass on Earth and, as such, have major roles in the recycling of elements vital to life."

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