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Biofilms A Book Review

Biofilms: A Book Review>

Mind Map branch: Biofilms A Book Review Biofilms A Book Review Most bacteria live in biofilms Biofilm bacteria cannot be cultured Most biofilms are multi-species consortia Some say 99% of all bacteria are not free Modern medicine is based on free bacteria activities Biofilms have survived millions of years They live wherever there is fluid flow and surface They adapt to changing conditions, exchanging DNA When a film is destroyed, it reforms or another one forms Biofilms have machine-like features They form on surfaces rapidly They have connecting wires They have efficient shapes and formations They contain channels for nutrient movement When some cells die, their parts are re-used Biofilm bacteria act differently than free bacteria In general they are not as toxic They produce a matrix to live in They are resistant to current antibiotics Free bacteria are much better understood Our immune cells cannot get through the matrix They signal back and forth with other bacteria, species Biofilms release free bacteria which our immune cells can destroy Links http://www.amazon.com/Biofilm-Primer-Springer-Biofilms/dp/3540680217 The Biofilm Primer http://www.erc.montana.edu/Res-Lib99-SW/Movies/Database/MD_DisplayScript.asp Movies http://video.google.com/videosearch?q=biofilms&emb=0&aq=0&oq=biofilm#q=biofilms&emb=0&aq=0&oq=biofilm&start=20 Google videos http://www.novamind.com/connect/nm_documents/460 Map: Biofilms Introduction We harness biofilms to perform work They provide food for higher life forms They break down material into biofuels They decontaminate oil spills and toxic dumps We have biofilms in/on our bodies Normal biofilms may protect us from disease bacteria Biofilms may build up on devices and not cause symptoms Biofilms may build up on implanted devices, causing symptoms Each mammalian species has its own species of biofilm bacteria There are normal biofilms on skin, G-I system, perineal/vaginal areas Normal biofilms can give way to symptomatic biofilms when body tissues change Some parts of the body -- internal organs, eyes -- protect themselves from biofilms

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PREVENTION OF PATHOGENIC BIOFILM DISEASES

Keep air conditioning systems clean
Use hygienic wound management
Use dental hygiene
Avoid unnecessary antibiotics
Prevent diabetes, minimize glycation
Minimize need for device implantation
Keep inflammation minimized

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AREAS OF
EXPECTED BIOFILMS

Skin
Teeth
Gums
Sinuses
Throat
Intestinal tract
Vaginal area
Urethra

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The Biofilm Primer
by J. William Costerton
Springer Series on Biofilms, 2007

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Only recently has the microscopic technology for visualization been developed which allows these tiny ecosystems to be studied. The book is an overview of biofilm behavior and the implications for science and medicine.

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Biofilms in Yellowstone, extreme contitions

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Staphlococcus biofilm

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Biofilms build on oil spills

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Biofilms in natural systems

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