2 Systems

Map Branches

• 3 Stages (Primary/Secondary is Curable/Treatable)
  • Primary
    • Hard Canker on site of invasion
      • 3-4 weeks after contact w/host
      • Painless
      • Crater Appearance w/Lymphadenopathy
        • Local Lymphandenopathy
          • Enlargement with or without pain
            • Typically Groin
        • Serological Test = Negative
          • No antibodies found against syphilis infection
  • Secondary
    • Appears 2 months after Primary Infection
      • Involves
        • Generalized Lymphadenopathy (not always visible)
          • Involves Groin & Cervical Area
          • Chronic Leptomeningitis Develops
        • Skin Rash
          • Papule/Pustule
          • Palms or Feet
          • Specific Rash
            • Wet and White
            • Wet portions of body
              • Vaginal Area
                • Condylomata Lata (Venereal Warts)
    • Very Contagious
    • Serological Tests = Highly Positive
    • Spread = Opening into blood stream
    • Last 2 months and subsides
  • Tertiary
    • Appears 10-15 yrs after secondary Subsides
    • 2 Systems
      • CardioVascular 80% (Aka Syphilitic Aortitis)
        • Dramatic change in Wall of Aorta (Ascending Arch)
        • Enlargement & Sclerotic Surface of Aorta Wall
          • Predisposition to Thrombus
          • Rough Surfaces promotes Platelets
        • Develops Aortic Insufficiency (syphilis #3 cause of this)
          • Low Diastolic Pressure
          • DeMusette's Syndrome (stetho on head jumps)
      • Neurosyphilis 10% (Aka Tabes Dorsalis)
        • Involves Brain and SC
          • Posterior Horn of SC (sensation)
          • Numbness and tingling (Nerve root compression/irritation)
        • Brain = Atrophy of Gray Matter
          • Loss of Cognitive Process
          • Called General Paresis (Aka General Paresis of Insane)
          • Chronic Subdural Hematoma
          • Gummateous Necrosis or
            • Liquifactive Necrosis or
              • Caseous Necrosis

Comments

► Comments for document "CNS Infections"

	Kathleen Sundmark almost 4 years ago	Great info. Lots of work. Thank you for these maps. They represent a lot of information and a great deal of work.

	Edward Shekhter almost 4 years ago	Re: Great info. Lots of work. Thank you. Just got NovaMind about 3 weeks ago. This is my first go at it. There is so much information, but I am not sure if the way I presented/did this is the best way. Also I am looking for more insight and better way to do these mind maps, from experienced people.

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